Cristiano Ronaldo, Gabriel Heinze, Louis Saha and Mikael Silvestre are all set to make their first pre-season appearances since returning from Germany.
John O'Shea also returns after an injury scare sustained in the Reds' triumphant LG Amsterdam Tournament campaign.
The more experienced players are accompanied to the Kassam Stadium by a healthy number of younger players, including Academy striker Sean Evans.
United: Foster, Heaton, Simpson, Bardsley, Heinze, O'Shea, Silvestre, Richardson, Miller, Fletcher, D Jones, R Jones, Martin, Ronaldo, Solskjaer, Saha, Rossi, S Evans.